epil.bugs {GLMMGibbs}R Documentation

Results of a Clinical trial of Progadine

Description

The dataset describes the results of the pre-crossover phase of a crossover trial of the effects of progadine, an anti-epileptic drug. Patients were assigned blindly and at random to receive either the drug or a placebo in addition to standard chemotherapy. Each patient visited the trial centre on four subsequent occasions, on each of which the number of seizures in the previous two weeks was recorded. Also recorded was the patient`s age, whether they were on treatment or placebo and the number of seizures suffered in the two-week period before the trial (known as the baseline seizures). The data is stored in the same format as in the BUGS example book

Usage

data(epil.bugs)

Format

[,1] y numeric(236) number of seizures (one observation per visit)
[,2] Trt numeric(59) whether the patient received Progadine (=1) or placebo (=0) (one observation per patient)
[,3] Base numeric(59) number of baseline seizures (one observation per patient)
[,4] Age numeric(59) Age (one observation per patient)

Source

Thall, P . F. and Vail, S. C. 1990, Some covariance models for longitudinal count data with overdispersion Biometrics, pages 657-671, volume 46.